This site is a prelude to the internationally supported BioCatalogue system that will collect, store, validate, and make available web-services in the biosciences. This registry is mainly meant for the EU projects EMBRACE, BioSapiens and ENFIN, but other users are welcome too. As a potential web service user, you can search or browse the registry for services that match your needs. Furthermore, each entry includes live test data, showing the current and historical status of the service. Each entry can also include example client software to help you include them in your own programs or workflows. As a service provider, the registry helps you build high quality services that conform to industry standards, and gives you a means of advertising your tools to the user community as well as a platform for testing your service. Your service remains your property and published by you - this registry merely advertises its existence and its status.
This system will in due time merge seamlessly into the BioCatalogue, and if you use this registry, you will not have to register your service again with the BioCatalogue.
About CorEx: How to infer from transcription data, which sets of transcription factors regulate a given group of genes, is a difficult task. Tackling this problem generally involves three steps: i) define the group of genes, ii) identify common transcription factor binding sites (TFBS) in the promoters of those genes, iii) test the identified TFBS for enrichment/sharing. CorEx offers web service that addresses each of these steps used either jointly or separately.
* Correlation mapping using multidimensional scaling (MDS)
mprap predicts the relative surface accessibility of a protein sequence. The predictor is optimized for membrane proteins.
engineDB is a repository for precalculated functional analogouse gene products using the gene ontology (GO) annotation to calculate the functional analogy by semantic similarity.
The GO data used are from the GO database version 08_09.
engineDB_08_09 is a web service accessing the engineDB searching for two gene groducts (UniProt primary accession number) the functional similarity indicating the coresponding raw score and p-value (see http://funcnet.eu)
MkDom2 is the program used routinely to build each new release of ProDom. The algorithm relies on the assumption that the shortest amino acid sequence corresponds to a single domain, and may be used as a query to screen the database with the psi-blast program, in order to cluster homologous domains. To build ProDom, we run this program on the UniProt (swissprot/trembl) Knowledge Database, but it can be run on any set of protein sequences in a fasta file.
- a file containing the sequences to analyse in fasta format